姓名：臧淩鶴
性别：女
籍貫：遼甯省沈陽
聯系電話：18341401186、13555829345
E-Mail：linghezang@sina.com
個人主頁：
職稱/職務：副教授
通訊☯⚜☯：沈陽市沈河區文化路103号
郵政編碼：110016
學習/工作經曆：
2009/09 - 2012/06，bevictor伟德，藥理學，博士，導師：池島喬
2007/09 - 2009/06，bevictor伟德，藥理學，碩士，導師：徐峰
2003/09 - 2007/06，bevictor伟德，藥物制劑，學士
2012/08 -至今， bevictor伟德，bevictor伟德，講師
2014/10 - 2015/03，日本武庫川女子大學，藥學部，訪問學者
研究方向：
體内外細胞及動物實驗模型，進行天然藥物抗腫瘤活性篩選及分子機制研究；腫瘤免疫及微環境探索等。新藥藥理藥效學及機制研究等。
兼職情況：
科研/獲獎情況：
華會明，劉偉偉，臧淩鶴，李達竑. Novel enmein-type diterpenoidhybrids coupled with nitrogen mustards: Synthesis of promising candidates for anticancer therapeutics. 沈陽市自然科技學術成果三等獎，2018.
臧淩鶴. “Oridonin purifiered from Chinese medical herb, Donglingcao, induced nitric oxide generation to promote the efferocytosis of apoptotic cells by hunman histocytic lymphoma U937 cells”, 中醫藥學會聯合會, 優秀論文獎, 優秀獎, 2012.
教學/指導研究生情況：
承擔本科生人體解剖學、人體解剖生理學理論及實驗教學工作；指導本科生畢業專題、大學生創新創業項目
發表論文/出版著作：
（1）Zang L., Wang J., Ren Y., Liu W., Yu Y., Zhao S., Otkur W., Zhao Y., Hayashi T., Tashiro SI., Onodera S., Ikejima T. Activated toll-like receptor 4 is involved in oridonin-induced phagocytosis via promotion of migration and autophagy-lysosome pathway in RAW264.7 macrophages.Int Immunopharmacol, 2018,11(66): 99-108. IF:3.188
（2）Zang L., He H., Xu Q., Yu Y., Zheng N., Liu W.,Hayashi T., Tashiro S., Onodera S., Ikejima T.*.Reactive oxygen species H2O2and •OH, but not O2•(-)promoteoridonin-induced phagocytosis of apoptotic cells by humanhistocyticlymphoma U937 cells.Int Immunopharmacol, 2013, 15(2): 414-423. IF:2.23
（3）Zang L., Xu Q., Ye Y., Li X., Liu Y.,Tashiro S., Onodera S., Ikejima T.*.Autophagy enhanced phagocytosis of apoptotic cells byoridonin-treated humanhistocyticlymphoma U937 cells.Arch Biochem Biophys, 2012, 518(1): 31-41. IF:3.78
（4）Zang L., He H., Ye Y., Liu W., Fan S.,Tashiro S., Onodera S., Ikejima T.*.Nitric oxide augmentsoridonin-inducedefferocytosisby humanhistocyticlymphoma U937 cells via autophagy and the NF-κB-COX-2-IL-1β pathway.Free Radic Res, 2012, 46(10): 1207-1219. IF:2.67
（5）He H.,Zang L.,Feng Y., Wang J., Liu W., Chen L., Kang N., Tashiro S., Onodera S., Qiu F.*, Ikejima T.*. Physalin A induces apoptotic cell death and protective autophagy in HT1080 human fibrosarcoma cells.J Nat Prod, 2013, 76(5): 880-888. IF:3.88
（6）He H.,Zang L.,Feng Y., Chen L., Kang N., Tashiro S., Onodera S., Qiu F.*, Ikejima T.*. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-kappa B survival pathway in A375-S2 cells.J Ethnopharmacol, 2013, 148(2): 544-555. IF:3.11
（7）Liu W., Otkur W., Li L., Wang Q., He H.,Zang L.,Hayashi T., Tashiro S., Onodera S., Xia M.*, Ikejima T.*. Interference of silibinin with IGF-1R signalling pathways protects human epidermoid carcinoma A431 cells from UVB-induced apoptosis.Biochem Biophys Res Commun, 2013, 432(2): 314-319. IF:2.55
（8）Liu W., Otkur W., Zhang Y., Li Q., Ye Y.,Zang L.,He H., Hayashi T., Tashiro S., Onodera S., Ikejima T.*. Silibinin protects murine fibroblast L929 cells from UVB-induced apoptosis through the simultaneous inhibition of ATM-p53 pathway and autophagy.FEBS J, 2013, 280(18): 4572-4584. IF:4.53
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